Judith B Zaugg

Biography
The main research interest of Judith Zaugg's research group at EMBL Heidelberg is to understand the molecular basis of complex genetic traits and diseases using genome-wide data of various molecular phenotypes, and developing multi-omics data integration approaches. Judith studied Chemical Biology at ETH Zurich and did her PhD at the EMBL-EBI in computational functional genomics, investigating non-canonical transcriptional regulatory mechanism in yeast. For her postdoc she went to Stanford University where she studied the genetic basis of regulatory variation across healthy human individuals, integrating multiple histone ChIP-Seq for multiple individuals with physical interactome data (Hi-C, ChIA-PET) to identify genetic associations between distal regulatory elements.
Keywords
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Papers
To get the community network started, we have populated the database with almost 2000 papers from PubMed which had clear connections to both systems biology and European institutes. Due to the automated nature of this search many relevant papers may be missing. Registered researchers can correct these mistakes by adding more of their own papers to their profiles, or removing the non-relevant ones.

Backmasking in the yeast genome: encoding overlapping information for protein-coding and RNA degradation.
Cakiroglu SA et al.
2016
Nucleic Acids Res
Data-driven hypothesis weighting increases detection power in genome-scale multiple testing.
Ignatiadis N et al.
2016
Nat Methods
SNPhood: investigate, quantify and visualise the epigenomic neighbourhood of SNPs using NGS data.
Arnold C et al.
2016
Bioinformatics
Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions.
Grubert F et al.
2015
Cell
Role of histone modifications and early termination in pervasive transcription and antisense-mediated gene silencing in yeast.
Castelnuovo M et al.
2014
Nucleic Acids Res
Extensive variation in chromatin states across humans.
Kasowski M et al.
2013
Science
Gene loops enhance transcriptional directionality.
Tan-Wong SM et al.
2012
Science
A genomic model of condition-specific nucleosome behavior explains transcriptional activity in yeast.
Zaugg JB et al.
2012
Genome Res
Bacterial adaptation through distributed sensing of metabolic fluxes.
Kotte O et al.
2010
Mol Syst Biol
N5-CAIR mutase: role of a CO2 binding site and substrate movement in catalysis.
Hoskins AA et al.
2007
Biochemistry

Speaker at

5 Jul 7 Jul 2017
The International Conference on Systems Biology of Human Disease (SBHD) is a transatlantic event ...
28 Oct 30 Oct 2015
Functional Genomics and Systems Biology: From Model Organisms to Human Health